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ea0063p718 | Pituitary and Neuroendocrinology 2 | ECE2019

A rare case of a TSH/GH secreting pituitary macroadenoma

Gogakos Apostolos , Efstathiadou Zoe , Tsirou Efrosini , Lypiridou Sofia , Mintziori Gesthimani , Kostopoulos Ioannis , Foroglou Nikolaos , Kita Marina

Introduction: Thyrotropin (TSH) secreting pituitary adenomas (TSHomas) are very rare and account for less than 2% of all pituitary adenomas. They present with elevated levels of fT4 and normal to high levels of TSH. About 25% of TSHomas co-secrete other anterior pituitary hormones. Growth hormone (GH) is the most commonly co-secreted hormone, followed by prolactin (PRL) and gonadotropins. Herein, we report a case of pituitary adenoma with simultaneous secretion of TSH and GH.<...

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ea0035p880 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Somatostatin analogue treatment of a TSH secreting adenoma presenting with accelerated bone metabolism and a pericardial effusion

Mousiolis Athanasios , Kotsa Kalliopi , Rapti Eleni , Yavropoulou Maria , Efstathiou Maria , Foroglou Nikolaos , Yovos Ioannis

Objective: To report the unusual presentation of a thyrotropinoma in a patient with: i) accelerated bone turnover, evident as osteopenia and increased serum alkaline phosphatase level, and ii) a pericardial effusion, years before diagnosis, that resolved completely following surgery and somatostatin analogue treatment.Case report: A 38-year-old man had been treated for years for presumed hypothyroidism with thyroxine supplementation based on elevated TSH...

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Endocrine Abstracts

A rare case of a TSH/GH secreting pituitary macroadenoma

Somatostatin analogue treatment of a TSH secreting adenoma presenting with accelerated bone metabolism and a pericardial effusion

BiosciAbstracts